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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUP153
All Species:
20.91
Human Site:
S498
Identified Species:
46
UniProt:
P49790
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49790
NP_005115.2
1475
153938
S498
S
P
E
I
T
T
S
S
P
S
P
I
N
S
S
Chimpanzee
Pan troglodytes
XP_001170682
1475
154026
S498
S
P
E
I
T
T
S
S
P
S
P
I
N
S
S
Rhesus Macaque
Macaca mulatta
XP_001096101
1474
153680
S498
S
P
E
I
T
A
S
S
P
S
P
I
N
S
S
Dog
Lupus familis
XP_535898
1478
153685
S499
S
S
V
I
T
T
S
S
P
A
T
I
S
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P49791
1468
152805
S498
S
P
A
I
S
A
A
S
S
S
S
V
S
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508163
1644
167929
S645
P
T
S
S
T
A
S
S
S
P
I
R
M
A
Q
Chicken
Gallus gallus
XP_418937
1473
153350
S501
S
L
P
I
S
T
A
S
L
A
P
F
N
F
S
Frog
Xenopus laevis
NP_001082284
1605
164952
N537
I
V
K
S
T
E
S
N
A
Q
S
P
G
S
S
Zebra Danio
Brachydanio rerio
XP_700317
1436
146282
S470
L
P
P
A
S
L
P
S
N
F
T
L
P
T
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793520
1708
174739
K568
T
S
R
S
S
S
I
K
P
S
P
A
Q
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14907
823
86497
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97.2
86.8
N.A.
N.A.
81.9
N.A.
62.8
64.5
43.7
43.5
N.A.
N.A.
N.A.
N.A.
26.5
Protein Similarity:
100
99.4
98.3
91.7
N.A.
N.A.
88.9
N.A.
72.2
75.6
58.5
57.7
N.A.
N.A.
N.A.
N.A.
42
P-Site Identity:
100
100
93.3
60
N.A.
N.A.
40
N.A.
20
46.6
26.6
13.3
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
93.3
73.3
N.A.
N.A.
66.6
N.A.
26.6
66.6
40
33.3
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
31.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
28
19
0
10
19
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
28
0
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
10
0
10
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
55
0
0
10
0
0
0
10
37
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
0
0
10
0
0
10
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
10
0
0
0
37
0
0
% N
% Pro:
10
46
19
0
0
0
10
0
46
10
46
10
10
19
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
10
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
55
19
10
28
37
10
55
73
19
46
19
0
19
46
73
% S
% Thr:
10
10
0
0
55
37
0
0
0
0
19
0
0
10
0
% T
% Val:
0
10
10
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _